Are Oats Part of a Safe Gluten-free Diet for Celiac Disease Patients?
Are oats part of a safe gluten-free diet for people on celiac disease? Photo: CC–R. Pavich
Celiac.com 05/01/2017 – To avoid symptoms, and promote full gut healing, people with celiac disease should follow a strict gluten-free diet. Oats might increase the nutritional value of a gluten-free diet, but their inclusion for people with celiac disease remains controversial, and data have been conflicting.
A team of researcher recently set out to determine the safety of adding oats to a gluten-free diet for patients with celiac disease. The research team included María Inés Pinto-Sánchez, Natalia Causada-Calo, Premysl Bercik, Alexander C. Ford, Joseph A. Murray, David Armstrong, Carol Semrad, Sonia S. Kupfer, Armin Alaedini, Paul Moayyedi, Daniel A. Leffler, and Elena F. Verdú.
They are variously affiliated with the Department of Medicine, Farncombe Family Digestive Research Institute, McMaster University in Hamilton, Ontario, Canada, the Leeds Gastroenterology Institute, St. James’s University Hospital in Leeds, UK, the Leeds Institute of Biomedical and Clinical Sciences at the University of Leeds in Leeds, UK, the Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester in Minnesota, US, the Celiac Disease Center at University of Chicago Medicine in Chicago, Illinois, US, the Celiac Disease Center at Columbia University, New York City, New York, US, and the Division of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, US.
For their systematic review and meta-analysis of clinical and observational studies, the team searched the Cochrane Central Register of Controlled Trials, MEDLINE, and EMBASE databases for clinical trials and observational studies on the effects of including oats in gluten-free diet of celiac patients. The studies reported patient symptoms, serology test results, and histologic assessments. The team used the GRADE approach to assess the evidence.
Out of 433 total studies, the team found 28 that met their criteria for analysis. Of these, 6 were randomized and 2 were not-randomized controlled trials comprising a total of 661 patients. The remaining studies were observational. All randomized controlled trials used pure, uncontaminated oats.
To provide a more authoritative conclusion, they call for clinical double-blind, placebo-controlled, randomized trials, using commonly available oats sourced from different regions.
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Jefferson Adams is a freelance writer living in San Francisco. His poems, essays and photographs have appeared in Antioch Review, Blue Mesa Review, CALIBAN, Hayden’s Ferry Review, Huffington Post, the Mississippi Review, and Slate among others.
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Published at Mon, 01 May 2017 15:30:00 +0000